Epub 2013 Jun 28. Background: This change to our approach will greatly benefit our patients. 2017;45(1):97105. Dont wait. Despite being a very common injury, until today, the only surgical treatment available for torn ACLs has been ACL reconstruction using allograft, autograft or suture-only repair. Registration: 2020 Feb;44(2):365-380. doi: 10.1007/s00264-019-04417-8. Patients with the implant had an average that was greater by 1.61 mm in the treated knee compared to their untreated knee. eCollection 2019 Mar. (6) Patterson MR, Delahunt E. A diagonal landing task to assess dynamic postural stability in ACL reconstructed females. At two years, control subjects had a laxity that, on average, was greater by 1.8 mm in the treated knee than that of the untreated knee. Zhang Y, Xu C, Dong S, Shen P, Su W, Zhao J. Arthroscopy. (HealthDay)An anterior cruciate ligament (ACL) implant that offers an alternative to traditional ACL reconstruction has received marketing authorization from the U.S. Food and Drug. This allows for ACL repair. 2 absorbable sutures attached to it is passed through the femoral tunnel and engaged on the proximal femoral cortex. Determining the Need for Surgery When You Feel Better Post-ACL Tear, Treating a Torn ACL Knee in Children and Teens, Surgery Treatments for Knee Pain and Injuries, Why Knee Arthritis Is Likely to Develop After an ACL Tear, Using Your Own Tissue vs. Donor Graft for ACL Surgery, Tympanoplasty Surgery: Everything You Need to Know, Meniscus Tears: Symptoms, Diagnosis, and Treatment. The agency also is responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products. All rights reserved. These initial studies demonstrated that even the first surgeries performed for this technique had similar outcomes to the current gold standard of ACL reconstruction with autograft tendon, and patients did not have to have a graft harvested from their leg, she says. The .gov means its official. . Regenexx Perc-ACLR has been performed since 2012. It can also be done via sutures, a medical device used to hold body tissues together. FDA authorizes marketing of new implant to repair a torn ACL. Failure rates for anterior cruciate ligament (ACL) repair are greater than those for ACL reconstruction. 2 nonabsorbable sutures (green sutures) and No. A total of 74 patients with acute proximal isolated ACL tears will be assigned in a 1:1 allocation ratio to either (I) ACL repair using cortical button fixation and additional suture augmentation or (II) ACL reconstruction using an all-inside autologous hamstring graft technique. Key Takeaways. Lower extremity compensatory neuromuscular and biomechanical adaptations 2 to 11 years after anterior cruciate ligament reconstruction. The U.S. Food and Drug Administration (FDA) approved a new implant that can repair some anterior cruciate ligament (ACL) injuries. (8) Nyland J, Klein S, Caborn DN. However, given that BEAR is a new technology, most surgeons are unlikely to allow a return to sports at six months. ________________________________________________________________. First, BEAR allows the ACL to repair itself rather than ripping out the ACL remnants and placing a tendon as a substitute. Is the BEAR Implant Safe? 2013 Oct;41(10):2340-6. doi: 10.1177/0363546513498998. The patient's own blood is injected into the implant during the surgical implantation procedure with the intent of forming a device-protected clot that enables the body's healing process. Before In a randomized controlled trial of 100 people who experienced complete ACL rupture, 65 received the implant and 35 members in a control group had reconstruction via autograft, using tendon from their own bodies. Every patient underwent physical therapy after surgery, and the team followed them for two years. Results: However, as shown above, just like an ACL reconstruction, the BEAR implant surgery still has the physician drill tunnels. government site. Kristen Fischer is a journalist who has covered health news for more than a decade. Knee Surg Sports Traumatol Arthrosc. The request was submitted under section 513(f)(2) of the FD&C Act. 2021 Feb 3;103 (3):e14. Please enable it to take advantage of the complete set of features! Its a multi-center, randomized, clinical trial seeking adult participants with a torn ACL that has occurred within the past 50 days, who qualify for surgery. The peripheral higher signal intensity (lighter gray) indicates increased higher water content in the tissues surrounding the repaired ACL. Epub 2020 Jun 25. 2019 Sep;53(18):1168-1173. doi: 10.1136/bjsports-2018-100167. Kristen Fischer is a journalist who has covered health news for more than a decade. Meaning the cartilage destruction markers after an ACL reconstruction surgery are similar to those seen right after the original injury, causing a double hit to the cartilage. 33,34 The scaffold is used to bridge the . Within about eight weeks of the BEAR Implant surgical procedure, it is absorbed and replaced by the bodys own tissue. Lu W, Deng Z, Essien AE, Arthur Vithran DT, Opoku M, Li Y, Xiao W. J Clin Med. Finally, returning to play is likely much quicker for a precise image-guided injection than the BEAR surgery. The BEAR Implant was granted De Novo Approval from the U.S. Food and Drug Administration in December 2020. Patients who had a bridge-enhanced ACL repair technique showed similar patient-report outcomes with no infection or rejection compared with patients who had autograft ACL reconstruction, according . eCollection 2021 Nov. Barnett S, Badger GJ, Kiapour A, Yen YM, Henderson R, Freiberger C, Proffen B, Sant N, Trainor B, Fleming BC, Micheli LJ, Murray MM, Kramer DE. The FDA granted marketing authorization for an implant to repair the injury. The Bridge-Enhanced ACL Repair (BEAR) Implant is an alternative to ACL reconstruction, which typically requires harvesting tendonsand sometimes bonefrom another part of the patients body or a deceased donor. Dr. Fadale: ACL tears are among the most common knee injuries. Patients must have an ACL stump attached to the tibia to construct the repair. Tian S, Wang B, Liu L, Wang Y, Ha C, Li Q, Yang X, Sun K. Am J Sports Med. Despite minor improvements to the procedure, clinical outcomes have not really changed. 2016 Nov 21;4(11):2325967116672176. doi: 10.1177/2325967116672176. Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction. Before sharing sensitive information, make sure you're on a federal government site. Although ACL reconstruction is effective, the procedure has drawbacks; the . -. 2019 Mar 22;7(3):2325967118824356. doi: 10.1177/2325967118824356. In the late 1990s, Martha Murray, MD, then an orthopedic surgeon with Boston Childrens Hospital, was researching why the ACL failed to heal on its own. Outcomes reported included International Knee Documentation Committee (IKDC) subjective and objective results, knee anteroposterior (AP) laxity findings via an arthrometer, and functional outcomes. Y.-M.Y. The https:// ensures that you are connecting to the FOIA Posterior cruciate ligament repair seems safe with low failure rates but more high level evidence is needed: a systematic review. Hypothesis: We hypothesized that patients treated with BEAR would have a noninferior . Dr. Owens: During the course of my career, we have seen some small incremental changes to the surgical techniques in ACL reconstruction. Arthrometry measures the difference in laxity between a person's healthy leg and their injured leg. Please enable it to take advantage of the complete set of features! Am J Sports Med. with the inherently same conflicts. -, Akelman MR, Fadale PD, Hulstyn MJ, et al. official website and that any information you provide is encrypted Effect of matching or overconstraining knee laxity during anterior cruciate ligament reconstruction on knee osteoarthritis and clinical outcomes: a randomized controlled trial with 84-month follow-up. This is a bovine collagen implant inserted in the torn area of the ACL with sutures placed in graft tunnels. The BEAR procedure is a new and different way of thinking about the surgical approach to treating ACL injuries. The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction. For the BEAR Trial Team, B.P. J Bone Joint Surg Am. Between 2006-2012, doctors and researchers with Rhode Island Hospital, Brown University, and Boston Childrens, collaborated for a series of preclinical studies that were performed to optimize the implant, to demonstrate the safety of its use in the body, and to show that it stimulated the ACL to heal. (13) Paterno MV, Rauh MJ, Schmitt LC, Ford KR, Hewett TE. This research study is approved by the FDA and funded by grants from the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Incidence of Second ACL Injuries 2 Years After Primary ACL Reconstruction and Return to Sport. BEAR-MOON is an acronym for BEAR (Bridge-Enhanced ACL Restoration) MOON (Multicenter Orthopaedic Outcomes Network). The patients also underwent arthrometry, a noninvasive measurement of laxityor loosenessof the knee joint. The Regenexx perc-ACLR procedure should be applied in patients that have a complete ACL tear, but the two ends are still connected. Vandenrijt J, Callenaere S, Van der Auwera D, Michielsen J, Van Dyck P, Heusdens CHW. Study design: The surgery, however, is not without its problems. Bookshelf U.S. Food and Drug Administration. Orthop J Sports Med. Hamstring strength indices were significantly higher in the BEAR group compared with the ACLR group (P = .0001). Home Blog The BEAR Implant for ACL Tears. Lower right panel: The sutures and extracortical buttons are secured. This new technique provides promise that soon surgeons will be able to repair and regenerate the ACL instead of replacing it. Background: This study assessed the safety of the newly developed bridge-enhanced anterior cruciate ligament (ACL) repair (BEAR), which involves suture repair of the ligament combined with a bioactive scaffold to bridge the gap between the torn ligament ends. Murray MM, Flutie BM, Kalish LA, Ecklund K, Fleming BC, Proffen BL, Micheli LJ. This action creates a new regulatory classification, which means that subsequent devices of the same type with the same intended use may go through the FDA's 510(k) premarket process, whereby devices can obtain marketing authorization by demonstrating substantial equivalence to a predicate device. Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive. Raquel Peat, Ph.D., MPH, USPHS, director of the Center for Devices and Radiological Healths Office of Orthopedic Devices, Todays marketing authorization provides new options for the hundreds of thousands of people affected by ACL rupture in the U.S. each year.. Arthroscopy. "Torn ACLs are among the most common knee injuries in the United States," according to Capt. Detailed Description: 2016 Sep;32(9):1887-904. doi: 10.1016/j.arthro.2016.03.008. (B) The scaffold is then saturated with 5 to 10 mL of the patients blood, and (C) the tibial stump is pulled up into the saturated scaffold. Lower left panel: The free suture ends (green) at the tibial end of the BEAR implant (which was positioned between the 2 ends of the torn ACL) are passed through the tibial tunnel to be tied over a second extracortical button. The device, the Bridge-Enhanced ACL Repair (BEAR) Implant, unlike traditional reconstruction, does not require the use of harvested tendons for ACL repair and is the only currently- available alternative to reconstruction with allograft, autograft or suture-only repair for the treatment of ACL rupture. ACL (anterior cruciate ligament) injuries. The experts explain how BEAR technology works and answer the most common questions about ACL injury and repair. 2021 Nov 9;9(11):23259671211052530. doi: 10.1177/23259671211052530. Cartilage. ACL injuries are among the most common knee injuries and affect around 400,000 Americans each year. J Orthop Res. A patient may recover strength faster after a BEAR than traditional ACLR. Tissue Eng Part A. The ACL implant isnt a traditional device like those used in most joint repairs. When typing in this field, a list of search results will appear and be automatically updated as you type. 2006;34(1):128135. The site is secure. Surgical techniques in the management of pediatric anterior cruciate ligament tears: Current concepts. Epub 2016 May 13. Recruitment for the BEAR II trial was initiated in May 2015, and enrollment was completed June 2016. Cision Distribution 888-776-0942 They had an average score of 88.9, while those who underwent traditional ACL repair had an average of 84.8. The results were excellent (more on those below). On June 4, 2020, FDA received your De Novo requesting classification of the BEAR (Bridge-Enhanced ACL Repair) Implant. The patients also underwent arthrometry, a noninvasive measurement of laxityor loosenessof the knee joint. 2018;26:1362-1366. Bethesda, MD 20894, Web Policies The BEAR Implant is absorbed by the body as the ACL heals. Epub 2019 Feb 8. 2018 Sep 3;16(1):246. doi: 10.1186/s12967-018-1623-3. 2013 Dec;20(6):532-6. doi: 10.1016/j.knee.2013.07.008. Epub 2020 Apr 16. Upper right panel: After a cortical button carrying free sutures (green) is passed up through the femoral tunnel, the BEAR implant is loaded onto them and soaked with up to 10 mL of autologous blood. Schedule an appointment with a BEAR-MOON trial physician and find out if you qualify for the trial. Am J Sports Med. February 2022. doi:10.1177/23259671211070542. HHS Vulnerability Disclosure, Help The most significant differences are that BEAR still requires surgery, and the Regenexx Perc-ACLR procedure is a precise image-guided injection. Third, while its unknown if knees repaired with BEAR retain their position sense, thats much more likely than the tendon graft placed by ACLR surgery. The FDA granted the marketing authorization to Miach Orthopaedics, Inc. Media Contact:Abby Capobianco, 240-461-9059Consumer Inquiries: [emailprotected], 888-INFO-FDA. Thank you, {{form.email}}, for signing up. The preliminary work is very promising, but with any new research, we need more data to confirm the early findings, Lepley says. Copyright Regenexx 2023. We think you need to have sufficient ACL tissue left to repair for the surgery with the implant to work, Murray says. Hypothesis: Am J Sports Med. For full product and risk information . L.J.M. The caveat about using the implant is that the technique is most effective if the ligament ruptures mid-substance, or about the middle of the ligament, to provide two ends that are able to be sutured together. Patients report more satisfaction in terms of pain, symptoms, and readiness. Orthop J Sports Med. Unable to load your collection due to an error, Unable to load your delegates due to an error. Psychological Readiness to Return to Sport at 6 Months Is Higher After Bridge-Enhanced ACL Restoration Than Autograft ACL Reconstruction: Results of a Prospective Randomized Clinical Trial. 2023 Feb 20;24(1):8. doi: 10.1186/s10195-023-00688-5. The BEAR Implant from Miach Orthopaedics was approved by the U.S. Food and Drug Administration in December 2020. maintained a conflict-of-interest management plan that was approved by Boston Childrens Hospital and Harvard Medical School during the conduct of the trial, with oversight by both conflict-of-interest committees and the institutional review board of Boston Childrens Hospital, as well as the US Food and Drug Administration. The BEAR implant is then injected with autologous whole blood. In Complete ACL Tears, Bridge-Enhanced ACL Repair Was Noninferior to ACL Reconstruction for Symptoms and Functioning and Knee Laxity at 2 Years. An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, FDA Authorizes Marketing of New Implant to Repair a Torn ACL, Office of Orthopedic Devices, Office of Product Evaluation and Quality. Murray points out that patients who incurred an ACL months ago or who have little ACL tissue left would be more likely to benefit from an ACL reconstruction, rather than this implant. official website and that any information you provide is encrypted BEAR is a new technique that uses a collagen scaffold instead of a graft to repair the ACL. BEAR may result in knee stability and patient-reported outcomes at 2 years sufficient to warrant longer term studies of efficacy in larger groups of patients. from 8 AM - 9 PM ET. National Library of Medicine Orthop J Sports Med. 2023 Mar 2;12(5):1999. doi: 10.3390/jcm12051999. The new implant instead is made of proteins that are an integral part of the healing process, Braden Fleming, PhD, a professor of orthopedics at Brown University involved in the research, tells Verywell. First, BEAR allows the ACL to repair itself rather than ripping out the ACL remnants and placing a tendon as a substitute. Upper left panel: A suture (purple) is placed through the tibial stump via a whipstitch and secured with 2 free sutures (green) to an extracortical button. The BEAR procedure is a promising technique that will likely meet these goals. A piece of hamstring or quadriceps tendon is harvested, and then graft tunnels are drilled into the femur and tibia. Scand J Med Sci Sports. 2023 Mar;51(3):NP12-NP14. ACL injuries affect between 100,000 to 200,000 people in the U.S. each year. PMID: 32558951. Dr. Hulstyn: Female athletes are at 2-8 times greater risk of primary ACL injury compared with males, even when controlling for sport and competition level. 2023 Apr 26;10(1):49. doi: 10.1186/s40634-023-00605-z. Historically, the repair method of just suturing the two ends together has not been very effective.". The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure: An Early Feasibility Cohort Study. Randomized controlled trial; Level of evidence, 1. (A) The torn anterior cruciate ligament (ACL) tissue is preserved. HHS Vulnerability Disclosure, Help The problem is that the recent research from Harvard shows that drilling these graft tunnels likely means a significant second severe inflammatory hit to the cartilage (2-4). Systemic Review of Anatomic Single- Versus Double-Bundle Anterior Cruciate Ligament Reconstruction: Does Femoral Tunnel Drilling Technique Matter? is an assistant editor for The American Journal of Sports Medicine, the spouse of M.M.M. Complications observed in the study consisted of graft or repair failure and the need for additional surgical procedures. Outcomes-including the IKDC Subjective Score, the side-to-side difference in instrumented AP knee laxity, and muscle strength-were assessed at 2 years by an independent examiner blinded to the procedure. All content provided in this blog, website, or any linked materials, including text, graphics, images, patient profiles, outcomes, and information, are not intended and should not be considered or used as a substitute for medical advice, diagnosis, or treatment. Annually in the United States, as many as 250,000 people suffer an ACL tear [2 . Verywell Health's content is for informational and educational purposes only. -. Conclusion: This site needs JavaScript to work properly. What if the anterior cruciate ligament (ACL) had the ability to repair itself? These include educational payments from Kairos Surgical (D.E.K., Y.-M.Y.) B.C.F. The implant is aimed at patients at least 14 years of age who have experienced a complete ACL rupture confirmed with magnetic resonance imaging (MRI) scan. The BEAR Implant was cleared by the U.S. Food & Drug Administration through the De Novo Pathway. Compared to traditional ACL reconstruction, the implant is a less invasive procedure that restores the knee's natural anatomy and function. M.M.M. One of the most important findings of her research is that performing an ACL repair is very difficult, and it explains why initial attempts in the 1970's and 1980's did not work . The BEAR Implant is indicated for skeletallymature patients at least 14 years of age with a complete rupture of the ACL, as confirmed by MRI. It is a . 2023 Feb;17(1):12-21. doi: 10.1177/18632521221149059. This action creates a new regulatory classification, which means that subsequent devices of the same type with the same intended use may go through the FDAs 510(k) premarket process, whereby devices can obtain marketing authorization by demonstrating substantial equivalence to a predicate device. Bridge-Enhanced Anterior Cruciate Ligament Repair Is Not Inferior to Autograft Anterior Cruciate Ligament Reconstruction at 2 Years: Results of a Prospective Randomized Clinical Trial. Furthermore, the 8 patients who converted from BEAR to ACLR in the study period and returned for the 2-year postoperative visit had similar primary outcomes to patients who had a single ipsilateral ACL procedure. (16) Centeno C, Markle J, Dodson E, Stemper I, Williams C, Hyzy M, Ichim T, Freeman M. Symptomatic anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow concentrate and platelet products: a non-controlled registry study. Migliorini F, Vecchio G, Eschweiler J, Schneider SM, Hildebrand F, Maffulli N. J Orthop Traumatol. Torn ACLs are among the most common knee injuries in the U.S., but for years, treatment has been limited to ACL reconstruction, which can be quite invasive and typically requires using tendon or a combination of tendon and bone from other parts of the body, or obtained from a tissue bank, to complete the reconstruction, said Capt. Fleming says the FDA approval was exciting news that provides a treatment alternative to ACL reconstruction that does not require removing the injured ligament and replacing it with a graft of tendon.. So far, so good, Fleming reports. When the trial showed that no major complications occurred, the FDA granted approval for a second study (BEAR II) comparing outcomes of patients receiving BEAR to those receiving ACL reconstruction graft (the gold standard). At 24 months, 9 of the 10 BEAR patients and 7 of the 10 ACLR patients completed a study visit. The BEAR Implant is the first medical advancement to enable your body to heal its own torn anterior cruciate ligament (ACL). Irradiated Hamstring Tendon Allograft Versus Autograft for Anatomic Double-Bundle Anterior Cruciate Ligament Reconstruction: Midterm Clinical Outcomes. -, Anderson AF, Irrgang JJ, Kocher MS, Mann BJ, Harrast JJ; International Knee Documentation Committee. Recovery will take months, and re-tearing is common in active individuals. PMID: 23962647. Conclusion: Bridge-enhanced ACL repair (BEAR) is a new FDA-approved procedure that allows a torn ACL to heal itself and does not require graft tissue to be taken from another part of the body. Recruitment for the BEAR MOON trial was initiated in September of 2021 and the study is currently underway. At that time, those with the implant reported on their outcomes using the International Knee Documentation Committee Subjective Score, a knee-specific patient-reported outcome measure. TheLifespan Orthopedics Institute is managing the only New England site, one of six across the nation, to conduct the trial with our partner physicians at University Orthopedics. No surgery, drilling, or graft tunnels are required. -, Ageberg E, Roos HP, Silbernagel KG, Thomee R, Roos EM. At the two-year mark, patients who received the BEAR Implant reported an average score of 88.6 and control subjects reported an average score of 84.6 using the International Knee Documentation Committee Subjective Score, a patient-reported outcome measure (questionnaire) that asks questions about symptoms related to pain and stiffness, sports activity and knee function. The site is secure. This site needs JavaScript to work properly. This double-bundle design ensures that the ACL can control the rotation of the tibia, an essential function in protecting the knee. CONSORT (Consolidated Standards of Reporting Trials) diagram detailing patient flow through the study. 2021 Jun;39(6):1281-1288. doi: 10.1002/jor.24783. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American, Office of Orthopedic Devices, Office of Product Evaluation and Quality, FDA Approves First Orally Administered Fecal Microbiota Product for the Prevention of Recurrence of Clostridioides difficile Infection. We hypothesized that female sex would have significantly worse early functional outcomes and higher retear rates following primary repair of the ACL enhanced with a tissue-engineered scaffold . These patients are currently being followed to determine long term outcomes. Clipboard, Search History, and several other advanced features are temporarily unavailable. The technique was approved by the Food and Drug Administration in late 2020 and has been used in a handful of patients at OHSU, beginning with the first case in Oregon this past February. 2020 08:00 AM Eastern Standard Time. Lifespan, Rhode Island's first health system, was founded in 1994 by Rhode Island Hospital and the Miriam Hospital. Given the promising results of the BEAR procedure in the BEAR I and BEAR II trials, two additional studies were approved by the FDA the BEAR III trial and the BEAR-MOON trial. To learn more about the BEAR-MOON trial or to schedule an appointment with a trial physician, email bear.trial@lifespan.org or call 1-401-649-1906. Keywords: 2017;45:97-105. Epub 2023 Apr 13. Functional hop testing results were similar in the 2 groups at 12 and 24 months after surgery. The bridge enhanced ACL restoration (BEAR) procedure provides the ability to perform primary repair of the acutely torn ACL's via utilization of a proprietary protein based scaffold. Additional stitching holds the device in place. 2010 Sep;26(9):1212-25. doi: 10.1016/j.arthro.2010.01.003. Knee. PMID: 23897997. Background: Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction. A doctor has to weigh which patients would be an ideal candidate to receive the implant over traditional ACL reconstruction. PMID: 30176875; PMCID: PMC6122476. J Exp Orthop. This quicker return to play likely represents a less severe tear type for Perc-ACLR and the use of more powerful bone marrow concentrate versus whole blood for BEAR. ACL tears are often treated with surgery called ACL reconstruction. -, Andernord D, Desai N, Bjornsson H, Ylander M, Karlsson J, Samuelsson K. Patient predictors of early revision surgery after anterior cruciate ligament reconstruction: a cohort study of 16,930 patients with 2-year follow-up. How is BEAR different than ACLR surgery? and transmitted securely. Today, the U.S. Food and Drug Administration granted marketing authorizationunder the De Novo premarket review pathwayfor an anterior cruciate ligament (ACL) implant . AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto. The patients were also measured using an arthrometer, which measures the range of movement in a joint. These promising results suggest that longer-term studies of this technique are justified. How The BEAR Implant Works To Heal ACL Tears Paul Norio Morton, MD 2023-03-12T17:47:17-10:00 October 13, 2022 | Comments Off on How The BEAR Implant Works To Heal ACL Tears The Bridged Enhanced ACL Repair ( BEAR ) implant is the first medical advancement to enable your body to heal its own torn anterior cruciate ligament (ACL). 1991;14(3):114120. One or more of the authors has declared the following potential conflict of interest or source of funding: This study received funding support from the Translational Research Program at Boston Childrens Hospital, the Childrens Hospital Orthopaedic Surgery Foundation, the Childrens Hospital Sports Medicine Foundation, the Football Players Health Study at Harvard University, and the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Diseases through grants R01-AR065462 and R01-AR056834. The advantages are: In past decade, we have published two MRI analysis case series demonstrating good healing of the ACL with the Perc-ACLR procedure (16,17). An erratum has been published: J Bone Joint Surg Am.
Middletown, Ct Football Roster,
Trauma And The Brain Handout For Clients,
Elin Hilderbrand Books In Order Printable List,
Articles B